Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua - Hallo sahabat Paket Lengkap Pendidikan Dasar, Pada Artikel yang anda baca kali ini dengan judul Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua, kami telah mempersiapkan artikel ini dengan baik untuk anda baca dan ambil informasi didalamnya. mudah-mudahan isi postingan Artikel Jp Farmasi dd 2018, yang kami tulis ini dapat anda pahami. baiklah, selamat membaca.

Judul : Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua
link : Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua

Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua

Abstrak: Breynia cernua (local name Katuk Hutan) is an Indonesian medicinal plant (family: Euphorbiace- ae) originated from Papua which have been used traditionally as alternative treatment for breast and cervical cancer. The objectives of this research were to investigate potential cytotoxic activity and phytochemical aspect test of B. cernua extract and its fractions. Extraction was performed by macera- tion using ethanol 96%, followed by successive fractionations. Phytochemical screening and in vitro cytotoxic activity test were obtained for extract and active fraction with Brine Shrimp Lethality Test (BSLT) method and MCF-7 tumor cell lines were assessed by 3-(4-5-dimethylthiazol-2yl)-2,5-diphe- nyl tetrazolium bromide (MTT) assay. The results from cytotoxic activity test of breast cancer MCF-7 cell line from ethanolic 96% extract and three fractions: n-hexane, ethylacetate and water fractions showed 246.841 ppm, 165.65 ppm, 562.57 ppm dan 713.78 ppm respectively meanwhile the IC50 value of doxorubicin as the positive control was 6 μM. TLC and phytochemical screening showed the pres- ence of alkaloids, terpenoid, avonoids and tannins compounds in this active plant.

Keywords: Antitumor, Breynia cernua, BSLT, MCF-7

Penulis: Septriyanto Dirgantara, Rosye H.R. Tanjung, Hendra K. Maury, Edy Meiyanto

Kode Jurnal: jpfarmasidd180231

Demikianlah Artikel Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua

Sekianlah artikel Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua kali ini, mudah-mudahan bisa memberi manfaat untuk anda semua. baiklah, sampai jumpa di postingan artikel lainnya.

Anda sekarang membaca artikel Paket Lengkap Cytotoxic Activity And Phytochemical Analysis Of Breynia Cernua From Papua dengan alamat link https://paketpendidikandasar.blogspot.com/2020/04/paket-lengkap-cytotoxic-activity-and.html

Share this post