Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy - Hallo sahabat Paket Lengkap Pendidikan Dasar, Pada Artikel yang anda baca kali ini dengan judul Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy, kami telah mempersiapkan artikel ini dengan baik untuk anda baca dan ambil informasi didalamnya. mudah-mudahan isi postingan Artikel Jp Farmasi gg 2017, yang kami tulis ini dapat anda pahami. baiklah, selamat membaca.

Judul : Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy
link : Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy

Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy

Abstract: Epidemiology of NSAIDs gastropathy is increasing as increase number of usage. From arthritis to cardiovascular events and cancer prevention, the versatility of NSAIDs is not questioned. However, no dose of NSAIDs is safe. No matter low dose, or single use, NSAIDs will cause gastric damage upto 3-7 days after use. In inflammation and healing process of gastropathy there are various proteins involved, but treatment with COX-2 and SRF are associated with an immediate healing and better quality of gastric mucosa. Cyclea barbata (miers.) has been declared as functional food for preventing and treatment gastropathy yet, its mechanism of actions have not yet clearly discovered. Hence the aim of this study is to analyze the effects of Cyclea barbata (miers.) ethanol extract to COX-2 and SRF in gastric tissue, in time series basis. Laboratory mice was induced with aspirin to produce gastropathy and then treated with Cyclea barbata (miers.) extract for 1, 3, 7, 10 or 14 days. Gastric tissue then harvested and analysed with elisa procedure to determine tissue SRF and COX-2 level. Treatment was proven to increase COX-2 and SRF higher than control group. This concludes one of Cyclea barbata (miers.) mechanism for NSAIDs gastropathy is by increasing tissue COX-2 and SRF.

Keywords: Aspirin-induced gastropathy, COX-2, SRF, NSAIDs

Author: Florence Pribadi,  Suhartati, Achmad Basori

Journal Code: jpfarmasigg170020

Demikianlah Artikel Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy

Sekianlah artikel Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy kali ini, mudah-mudahan bisa memberi manfaat untuk anda semua. baiklah, sampai jumpa di postingan artikel lainnya.

Anda sekarang membaca artikel Paket Lengkap Pharmacodynamics Study Of Ethanol Extract Of Cyclea Barbata (Miers.) Leaves On Srf And Cox-2 Gastric Mice With Nsaid Gastropathy dengan alamat link https://paketpendidikandasar.blogspot.com/2020/03/paket-lengkap-pharmacodynamics-study-of.html

Share this post